RESEARCH INVESTIGATOR SR
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Posted Job Title
RESEARCH INVESTIGATOR SR
Perelman School of Medicine
PA-Pathology & Laboratory Medicine
Posted to the Web
Posted Job/Salary Grade
Contingent Upon Funding
Position End Date
The Senior Research Investigator (SRI) will be responsible for running a research program in the field of immunology, inflammation in the laboratory of Professor John D. Lambris. The position involves experimental design and applied immunology, pharmacology, and molecular and cell biology in complement research to develop novel methodologies for complement inhibition. The SRI will be required to use state of the art Fluorescence Resonate Energy Transfer (FRET), yeast two-hybrid, molecular cloning, confocal microscopy, siRNA, shRNA, ChiP, EMSA, and qPCR methodology, contribute to in vivo analysis, and investigate the mechanism of complement inhibition in the presence of small molecules. The SRI will supervise and teach students, coordinate research activities for the lab projects planning, develop innovative approaches, analyze and interpret data, contribute to manuscript and research proposal writing, give presentation at scientific conferences, and collaborate with other scientists as a member of a multi-disciplinary team. The position will require a level of independent thought and expertise that can only be obtained after substantial postdoctoral training.
Applicants must have a doctoral degree in Pharmacology, Biochemistry, or a related discipline and at least 5 to 7 years of substantial expertise in diacylglycerol signaling and receptor tyrosine kinase and G protein coupled receptor pathways. Candidates should have extensive experience in cell signaling, molecular biology, cell biology, immunology, and pharmacology, along with the ability to use and develop new approaches, such as yeast two-hybrid, FRET, chromatin immunoprecipitation (ChiP), EMSA, and qPCR assays to analyze cell signaling pathways, transcriptional regulation, and protein-protein and DNA-protein interactions. Furthermore, a strong publication record is required. Excellent written and oral communication skills and the ability to work independently as well as with collaborators are considered key qualifications. Position is contingent on continued funding.
Affirmative Action Statement
Background Check Required
http://jobs. hr. upenn. edu/postings/5658
Posting Supplemental Questions
Required fields are indicated with an asterisk (*).
How did you hear about this employment opportunity?
+ Public Job Posting
+ Internal Job Posting
+ Agency Referral
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What is your highest level of education?
+ Less than high school education
+ High School Diploma or GED
+ Vocational or Technical School
+ Associate's Degree or Two Year College
+ Bachelor's Degree
+ Master's Degree
+ PHD/MD/JD or equivalent doctoral degree
How many years of experience do you have related to this position?
+ 0 to 1 Year
+ 1 to 2 Years
+ 2 to 3 Years
+ 3 to 5 Years
+ 5 to 7 Years
+ 7 to 10 Years
+ Over 10 Years
A background check may be required for this position. Do you agree to allow a background check to be performed as a condition of employment?
Do you have experience with diacylglycerol signaling and receptor tyrosine kinase and G protein coupled receptor pathways?
Do you have extensive experience in cell signaling, molecular biology, cell biology, immunology, and pharmacology?
Do you have the ability to use and develop new approaches, such as yeast two-hybrid, FRET, chromatin immunoprecipitation (ChiP), EMSA, and qPCR assays to analyze cell signaling pathways, transcriptional regulation, and protein-protein and DNA-protein interactions?
Do you have a strong publication record?
+ Cover Letter